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Along with their useful effects Esomeprazole can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. What should you watch for while taking Esomeprazole? Esomeprazole works best if taken on an empty stomach at least one hour before meals and at the same time every day. Esomeprazole reduce the production of acid in the stomach. What should you watch for while taking Esomeprazole? If Nexium gives you an allergic reaction, you will not be able to take Nexium, or you have ever had an allergic reaction, you will not be able to take Nexium.

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