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Ask your doctor, nurse, or pharmacist any questions you may have about this medicine. Celecoxib should only be used in pregnant women when the benefits outweigh the potential risk to the fetus. This may cause an accidental overdose. When taking Celebrex, it is important to keep taking it as instructed by your doctor. Celebrex is used to reduce pain and inflammation in osteoarthritis, rheumatoid arthritis, acute pain, painful menstruation and menstrual symptoms, and to reduce numbers of colon and rectum polyps in patients using high doses of Celebrex, you should know that it is a capsule and it cannot be split in half.